Background: Both prevalence of the cancer and allergies cases are rising globally. Atopy has been speculated to have an impact on risk of various malignancies. Methods: In current study, the presence of allergens was tested in 1525 cancer. On the basis of a retrospective study of the procedures of allergy diagnostic performed on individuals who has already received a cancer diagnosis, allergies were confirmed. In accordance with pertinent guidelines, bronchial asthma and allergic rhinitis were also assessed in all patients. For comparison of patients of a control group that does not have experience cancer diagnoses. Results: In comparison to the control group, cancer patients had significantly less IgE-mediated allergy disorders. The ORs (odds ratios) for the allergic rhinitis, bronchial asthma, and atopic dermatitis for oncological group that is compared with non-cancer group of patients are 0.67 (95 percent confidence interval 0.52 to 0.81), 1.03 (95 percent CI 0.91 to 1.13), and 0.89 (95 percent CI 0.78 to 0.99) respectively. In comparison to patients in control group, the study population of patients of cancer had considerably lower mean concentrations of serum of the total IgE (45.98 14.9 verses 83.2 40.1 IU/l where the p < 0.05). The type of malignancy that was identified and the type of allergy did not significantly correlate. Conclusion: The observed correlation might point to the link between the IgE-mediated allergies and a decreased incidence of specific malignancies. Patients in the oncological trial had a low prevalence of allergic rhinitis, in particular. Our findings need to be confirmed by further research. In addition, compared to people with allergies, cancer patients typically have a worse socioeconomic background.
Keywords: Allergies, Cancer, Allergic Rhinitis, Types of Cancer, Incidence of Allergies