Background: Though the troponin is now most widely utilized biomarker, it cannot differentiate between subtypes of myocardial infarction and is not a specific marker for this condition. Earlier research has demonstrated that proteins referred to as myocardial infarction markers may be used to categorise different types of myocardial infarction. It is essential to categorize the myocardial infarction by the sub-type for proper care of patient. Aim: This study’s objective is to find the markers that can differentiate the type-1 myocardial infarction from other conditions when troponin is increased. Method: We found additional potential disease categorization markers by comparing type-1 MI to other illnesses defined by the raised troponin levels using the mass spectrometry. We then confirmed these indicators, in addition to those previously linked to plaque rupture and cardiovascular disease. We found serotransferrin, corticosteroid-binding globulin, and α-1 acid glycoprotein 2 as possible diagnostic indicators. Conclusion: We have found three distinct markers in our study that could successfully differentiate the type-1 myocardial infarction from other troponin-rising illnesses. To diagnose specifically the type 1 MI, it may be helpful to have these markers present along with additional data from complementary diagnostic procedures such chest discomfort, ECG, and troponin levels.
Keywords: Troponin-Elevated Diseases, Elevated Cardiac Troponin, Type 1 Myocardial Infarction, Mass Spectrometry, Proteomics