Objective: Little is known regarding the size of the difference in triglycerides between those who fast and those who don’t, or if this difference is influenced by certain possible risk factors for cardiovascular disease (CVD). Methods: Between 2018 and 2023, an 8,073-participant cross-sectional research was done to examine the distinctions between non-fasting and fasting triglycerides and their possible correlation with risk factors for cardiovascular disease (CVD). According to whether or not they were fasting, participants were split into two groups. The variation between non-fasting and fasting triglycerides and their correlation with CVD risk variables were estimated using linear regression models. Results: After controlling for confounders, it was discovered that individuals who fasted had lower triglycerides than those who did not, with a difference of 4.22 mg/dL that was statistically significant. The presence of hypertension, the usage of antihyperlipidemic medications, and LDL cholesterol levels were observed to impact the difference in triglyceride levels between fasting and non-fasting. The difference was more pronounced in those with hypertension, antihyperlipidemic medication use, or levels of LDL cholesterol below 130 mg/dL. Conclusions: The average sample showed a 4 mg/dL difference in triglycerides between non-fasting and fasting, and the presence of hypertension, the usage of antihyperlipidemic drugs, and LDL cholesterol levels all influenced the size of the changes. These findings may facilitate the accurate estimation of CVD risk utilising non-fasting and fasting triglycerides.
Keywords:Fasting, Triglyceride, Cardiovascular