Measurement of Fetomaternal Outcome in Patients with Sepsis in Pregnancy

Dr Asma Jabeen, Dr Zillehuma, Dr Sadiq Jan, Dr. Adila Anwar, Dr. Tanzila Aftab, Dr Rukhsana Shaheen Afzal, Dr Zafreen Naz Gudaro, Kashif Lodhi
Pharmacology (2024) Volume 109, Issue 2: 59-68

Objective: This research aims to assess the outcomes for both the fetus and the mother in cases where sepsis occurs during pregnancy. Materials & Methods: This research, spanning from January 2021 to January 2022 at our institution, encompassed a one-year duration. It involved the inclusion of 120 pregnant females who experienced sepsis at any point during their gravid period, irrespective of the need for hospitalization. The primary goal was to assess the outcomes for both the fetus and the mother among these gravid patients. Results: A total of 120 females presenting symptoms of sepsis, such as fever, were assessed for Fetomaternal outcomes. Among them, approximately 100 patients required hospitalization leading to the delivery of the baby, while the remaining twenty underwent follow-up through outpatient visits until delivery. These patients exhibited diverse causes for sepsis, with 70 (58.33%) experiencing sepsis due to PPROM (pre-term premature rupture of membranes), 25 (20.83%) developing sepsis from UTI, and 15 (12.5%) contracting sepsis as a result of pulmonary infection. Additionally, nine (7.5%) patients encountered sepsis from GIT infection, and one (0.08%) experienced stillbirth. Conclusion:  Sepsis during pregnancy presents a grave medical concern, carrying substantial risks for both the expectant mother and the growing fetus. This condition represents a potentially life-threatening reaction to an infection, capable of causing organ failure and mortality unless promptly identified and addressed.
 Keywords: Sepsis, Maternal Sepsis, Fetomaternal Outcome, Pregnancy.