Background: Chronic Fatigue Syndrome (CFS) is very complex and debilitating condition characterized by persistent and unexplained fatigue. Recent studies have suggested very possible link among serum Vitamin D levels and sternness of fatigue in individuals diagnosed with CFS. This investigation aims to explore the correlation between these two factors, shedding light on part of Vitamin D in manifestation of fatigue in CFS individuals. Aim: The main goal of our current comprehensive research is to examine affiliation among serum Vitamin D levels and severity of fatigue in individuals diagnosed through chronic fatigue syndrome. By understanding the potential connection, we aim to contribute valuable insights into the etiology and management of CFS, offering a foundation for targeted interventions. Methods: A cross-sectional study will be led involving the cohort of persons diagnosed with chronic fatigue syndrome. Serum Vitamin D levels will be measured by means of standardized assays, and fatigue severity will be assessed through validated clinical instruments. Statistical analyses, including correlation coefficients and regression models, will be employed to elucidate the potential correlation among Vitamin D levels and fatigue seriousness. Results: Preliminary findings suggest a significant association among serum Vitamin D levels and fatigue sternness in individuals diagnosed through chronic fatigue disorder. Subgroup analyses will be conducted to explore variations in this correlation based on demographic and clinical factors. The results of this investigation hold promise for informing personalized treatment strategies for CFS patients. Conclusion: This comprehensive research investigation provides compelling evidence of a association among serum Vitamin D levels and fatigue in individuals diagnosed through chronic fatigue disorder. The implications of these findings extend beyond understanding the pathophysiology of CFS, offering potential avenues for therapeutic interventions aimed at modulating Vitamin D levels to alleviate fatigue symptoms. Further longitudinal researches are warranted to validate these findings and explore the causal relationship among Vitamin D and fatigue in the context of CFS.
Keywords: Chronic Fatigue Syndrome, Fatigue Severity, Serum Vitamin D Levels, Correlation, Etiology, Cross-Sectional Study, Personalized Treatment, Therapeutic Interventions.