Background: Malignant pleural effusion (MPE) poses a significant challenge in clinical practice, necessitating a comprehensive understanding of its clinical profile for effective management. This study aimed to explore the clinical characteristics of patients presenting with MPE at hospital. Aim: The primary objective was to analyze and document the clinical features, demographic details, and associated factors in patients diagnosed with MPE, providing valuable insights for improved diagnosis and treatment strategies. Methods: A retrospective analysis was conducted on a cohort of patients with MPE. Duration of Study is July 2018 to June 2021 at Nishtar Medical University Multan. Clinical records, radiological findings, and laboratory results were reviewed to extract relevant data. Demographic information, comorbidities, presenting symptoms, diagnostic modalities employed, and treatment approaches were meticulously documented. Results: The study included 150 patients diagnosed with MPE during the specified period. Common presenting symptoms included dyspnea, cough, and chest pain. The majority of cases were associated with underlying malignancies such as lung cancer, breast cancer, and mesothelioma. Diagnostic modalities, including imaging studies and pleural fluid analysis, were employed for accurate identification of MPE etiology. Conclusion: The clinical profile of patients presenting with MPE in our Hospital reflected a diverse range of underlying malignancies. Early recognition and a multidisciplinary approach are crucial for timely intervention and improved patient outcomes. The findings underscore the importance of a thorough diagnostic workup and tailored treatment strategies based on the specific characteristics of each case.
Keywords: Malignant pleural effusion, clinical profile, retrospective analysis, diagnostic modalities, multidisciplinary approach, Hospital.